Discover Preclinical Drug Discovery: High Throughput Screening and Compound Progression Strategies (RSC Drug Discovery) by David P. Rotella.
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Overview: This book is one of a three-volume set that provides theoretical, practical and troubleshooting guidelines on all aspects of the pre-clinical Drug Discovery process. There is particular focus on the design, development and role of screening assays in Drug Discovery, including new developments and future trends, the main assay types utilized in screening campaigns, and the methods utilized in enabling the progression of "Hits" to "Leads" and "Candidates" The books will also fill current gaps in the literature such as primary, stem cell and other novel assay methods. Other relatively new research areas included are siRNA, high content screening, protein-protein interactions, pathway assays, non micro-titre plate based assays, label free assays, IT tools, approaches to identify biopharmaceuticals, emerging models and future trends in Drug Discovery.
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David P. Rotella writes contemporary fiction and has always been fascinated by character-driven stories. They hold a degree in English Literature and previously worked as an editor before transitioning to writing their own books. David P. Rotella lives with their spouse and a very vocal rescue cat.
Such a great read. I got really invested in the main character's journey. Everything just clicked for me. Worth the time and money.
Margaret SmithFebruary 14, 2024
Glad someone recommended this to me. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Would probably read it again at some point.
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Richard TorresMarch 26, 2024
It was okay. The pacing was a bit slow and I found myself skimming a few pages. It wasn't terrible, just okay. It's fine if you have nothing else to read.
Daniel ThomasNovember 20, 2025
Took me a few chapters to get into it, but it was worth it. I liked the main character, though some of the side plots were just okay. A solid 4 stars from me.
Ryan RobertsJuly 02, 2025
Pretty good overall. I liked the main character, though some of the side plots were just okay. A solid 4 stars from me.
Steven GreenMarch 23, 2025
An average read for me. It had some good moments, but the overall plot felt a bit disjointed in the second half. Just right down the middle.
Margaret PerezJuly 25, 2025
Glad someone recommended this to me. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. A solid 5/5 for me.
George AllenJanuary 31, 2025
Really enjoyed this one. The author did a great job wrapping everything up at the end. No weird plot holes left behind. A solid 5/5 for me.
Ashley AndersonJune 12, 2025
Really enjoyed this one. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Will be looking for more from this author.
Dorothy GarciaOctober 05, 2025
It was just alright. It had some good moments, but the overall plot felt a bit disjointed in the second half. It's fine if you have nothing else to read.
Jacob TaylorApril 17, 2024
Such a great read. I loved how the story unfolded. It kept me guessing without being too confusing. Will be looking for more from this author.
Laura WilliamsJuly 25, 2024
I have mixed feelings about this one. The pacing was a bit slow and I found myself skimming a few pages. It wasn't terrible, just okay. It's fine if you have nothing else to read.
Sandra TurnerOctober 09, 2025
Finished it in a couple of days. The writing style is very engaging. It’s easy to follow but still has a lot of depth. A solid 5/5 for me.
Elizabeth AndersonJanuary 07, 2024
I was pleasantly surprised. I got really invested in the main character's journey. Everything just clicked for me. Would probably read it again at some point.
John LeeDecember 26, 2024
Honestly one of the better books I've read lately. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Glad I picked this up.
Anthony RobinsonMarch 19, 2024
A very satisfying read. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. A solid 5/5 for me.
Sarah HernandezJune 13, 2024
Really enjoyed this one. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Would probably read it again at some point.
Laura TaylorSeptember 09, 2025
Glad someone recommended this to me. I got really invested in the main character's journey. Everything just clicked for me. A solid 5/5 for me.
Christopher CarterApril 14, 2025
Glad someone recommended this to me. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Definitely recommend it if you like this genre.
Deborah RodriguezNovember 30, 2024
A very satisfying read. I got really invested in the main character's journey. Everything just clicked for me. Definitely recommend it if you like this genre.
David ReyesDecember 28, 2025
A very satisfying read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Definitely recommend it if you like this genre.
Karen ReyesApril 03, 2025
Finished it in a couple of days. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Would probably read it again at some point.
Jacob TaylorSeptember 06, 2025
A very satisfying read. I got really invested in the main character's journey. Everything just clicked for me. Will be looking for more from this author.
Deborah TaylorMay 25, 2024
Such a great read. I loved how the story unfolded. It kept me guessing without being too confusing. Glad I picked this up.
Donald CollinsAugust 03, 2025
A very satisfying read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Will be looking for more from this author.
Susan ScottJuly 25, 2024
I was pleasantly surprised. I got really invested in the main character's journey. Everything just clicked for me. Would probably read it again at some point.
Donald LopezApril 09, 2024
A very satisfying read. The author did a great job wrapping everything up at the end. No weird plot holes left behind. A solid 5/5 for me.
Carol KingDecember 22, 2024
Really enjoyed this one. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Glad I picked this up.
Joshua PerezDecember 26, 2025
I was pleasantly surprised. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Definitely recommend it if you like this genre.
Donald LopezDecember 12, 2025
I was pleasantly surprised. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Would probably read it again at some point.
Deborah PerezMarch 30, 2025
I was pleasantly surprised. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Would probably read it again at some point.
Linda TaylorNovember 07, 2025
Good, but not quite perfect. I liked the main character, though some of the side plots were just okay. I'd probably recommend it to a friend.
James TurnerMay 06, 2024
A solid read. The middle dragged a tiny bit, but the ending totally made up for it. Not bad at all.
Cynthia RobertsOctober 12, 2025
A solid read. Writing is good, just wish there was a bit more depth in certain parts. Still kept my attention though. I'd probably recommend it to a friend.
Cynthia SanchezJanuary 12, 2025
Honestly one of the better books I've read lately. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Glad I picked this up.
Mary PhillipsApril 30, 2024
I was pleasantly surprised. The pacing was spot on and the characters felt real. I didn't find myself getting bored at any point. Definitely recommend it if you like this genre.
Michelle CampbellFebruary 12, 2024
Good, but not quite perfect. Interesting premise and executed fairly well. Just a few slow chapters here and there. Not bad at all.
Joshua PerezJuly 08, 2024
Pretty good overall. Writing is good, just wish there was a bit more depth in certain parts. Still kept my attention though. Not bad at all.
Amanda JohnsonMay 16, 2024
Honestly one of the better books I've read lately. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Worth the time and money.
Elizabeth RobinsonNovember 10, 2025
A solid read. Interesting premise and executed fairly well. Just a few slow chapters here and there. Still a good book.
Kevin BrownMarch 12, 2025
Glad someone recommended this to me. I got really invested in the main character's journey. Everything just clicked for me. Would probably read it again at some point.
Charles CollinsJuly 04, 2025
Such a great read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Worth the time and money.
Kevin MillerJune 29, 2024
Finished it in a couple of days. I loved how the story unfolded. It kept me guessing without being too confusing. Would probably read it again at some point.
Linda MartinJanuary 18, 2025
Finished it in a couple of days. I got really invested in the main character's journey. Everything just clicked for me. Will be looking for more from this author.
Laura CollinsJanuary 06, 2025
A solid read. It held my attention, even if a few things were a little predictable. Enjoyable weekend read.
Kevin MillerOctober 08, 2024
Such a great read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Definitely recommend it if you like this genre.
Cynthia SanchezMay 17, 2024
Finished it in a couple of days. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Worth the time and money.
Ashley AndersonJuly 09, 2024
A very satisfying read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Worth the time and money.
Edward TurnerJune 20, 2024
Finished it in a couple of days. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Worth the time and money.
Susan GonzalezMarch 07, 2024
Pretty good overall. The middle dragged a tiny bit, but the ending totally made up for it. Not bad at all.
Kevin DavisFebruary 24, 2025
I have mixed feelings about this one. It had some good moments, but the overall plot felt a bit disjointed in the second half. Just right down the middle.
Mary AndersonMay 11, 2024
Finished it in a couple of days. I loved how the story unfolded. It kept me guessing without being too confusing. Worth the time and money.
Christopher MartinDecember 30, 2025
Pretty good overall. Interesting premise and executed fairly well. Just a few slow chapters here and there. Still a good book.
Robert WrightMay 22, 2024
I was pleasantly surprised. I loved how the story unfolded. It kept me guessing without being too confusing. Would probably read it again at some point.
Linda TurnerOctober 09, 2024
It was okay. It had some good moments, but the overall plot felt a bit disjointed in the second half. Probably won't read it again, but it was an okay way to pass the time.
Nicholas PhillipsDecember 05, 2025
Pretty good overall. It held my attention, even if a few things were a little predictable. Not bad at all.
Donald WilliamsJuly 03, 2025
Such a great read. I loved how the story unfolded. It kept me guessing without being too confusing. Glad I picked this up.
Paul HillJanuary 09, 2025
I liked it for the most part. Writing is good, just wish there was a bit more depth in certain parts. Still kept my attention though. Not bad at all.
Ryan DiazJune 12, 2025
I was pleasantly surprised. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Worth the time and money.
Cynthia LeeOctober 04, 2025
Glad someone recommended this to me. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Worth the time and money.
Anthony BakerFebruary 12, 2024
A very satisfying read. I got really invested in the main character's journey. Everything just clicked for me. Glad I picked this up.
Sarah MartinezApril 30, 2025
I was pleasantly surprised. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Glad I picked this up.
Michelle PhillipsFebruary 03, 2025
Such a great read. The pacing was spot on and the characters felt real. I didn't find myself getting bored at any point. Glad I picked this up.
Jacob ScottOctober 19, 2024
A solid read. I liked the main character, though some of the side plots were just okay. Still a good book.
Donald CollinsAugust 22, 2025
A solid read. Interesting premise and executed fairly well. Just a few slow chapters here and there. A solid 4 stars from me.
Deborah DavisSeptember 14, 2024
Finished it in a couple of days. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Definitely recommend it if you like this genre.
Joshua RobertsJanuary 26, 2025
Finished it in a couple of days. The author did a great job wrapping everything up at the end. No weird plot holes left behind. A solid 5/5 for me.
Jacob ThompsonJune 28, 2024
Pretty good overall. Interesting premise and executed fairly well. Just a few slow chapters here and there. Not bad at all.
Cynthia ScottOctober 05, 2024
A solid read. Interesting premise and executed fairly well. Just a few slow chapters here and there. Still a good book.
Gary WilsonAugust 23, 2025
Really enjoyed this one. I loved how the story unfolded. It kept me guessing without being too confusing. Worth the time and money.
Susan CarterSeptember 30, 2024
Such a great read. The pacing was spot on and the characters felt real. I didn't find myself getting bored at any point. Glad I picked this up.
Carol WalkerAugust 18, 2025
I was pleasantly surprised. The writing style is very engaging. It’s easy to follow but still has a lot of depth. A solid 5/5 for me.
Deborah WilliamsDecember 08, 2025
Such a great read. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Glad I picked this up.
David ReyesJune 02, 2025
Such a great read. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Worth the time and money.
Robert WrightJune 08, 2025
It was just alright. The writing was fine, but I didn't feel very connected to the characters. They felt a bit flat. Might work better for someone else, just wasn't completely for me.
Deborah TaylorJune 10, 2025
A very satisfying read. I loved how the story unfolded. It kept me guessing without being too confusing. Would probably read it again at some point.
Charles ThompsonSeptember 26, 2025
Really enjoyed this one. I got really invested in the main character's journey. Everything just clicked for me. Would probably read it again at some point.
Thomas JohnsonSeptember 21, 2025
A very satisfying read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Worth the time and money.
Sandra ThomasApril 29, 2024
I was pleasantly surprised. I loved how the story unfolded. It kept me guessing without being too confusing. Definitely recommend it if you like this genre.
James MitchellDecember 29, 2025
Took me a few chapters to get into it, but it was worth it. Interesting premise and executed fairly well. Just a few slow chapters here and there. Not bad at all.
Deborah HillMay 22, 2024
Glad someone recommended this to me. I loved how the story unfolded. It kept me guessing without being too confusing. Would probably read it again at some point.
Kevin DavisMay 20, 2024
I was pleasantly surprised. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Definitely recommend it if you like this genre.
Rebecca GreenMarch 07, 2025
Not bad, but not my favorite. It had some good moments, but the overall plot felt a bit disjointed in the second half. It's fine if you have nothing else to read.
Charles RobinsonMay 23, 2025
Honestly one of the better books I've read lately. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Definitely recommend it if you like this genre.
Anthony FloresFebruary 04, 2025
Honestly one of the better books I've read lately. I got really invested in the main character's journey. Everything just clicked for me. A solid 5/5 for me.
George LopezAugust 12, 2025
Finished it in a couple of days. I loved how the story unfolded. It kept me guessing without being too confusing. Worth the time and money.
Elizabeth AndersonJanuary 05, 2024
Such a great read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Definitely recommend it if you like this genre.
Kenneth FloresJanuary 14, 2025
Glad someone recommended this to me. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Would probably read it again at some point.
Stephanie BrownApril 20, 2024
A solid read. It held my attention, even if a few things were a little predictable. Still a good book.
Ryan RamirezNovember 13, 2024
Such a great read. I loved how the story unfolded. It kept me guessing without being too confusing. A solid 5/5 for me.
Elizabeth WrightAugust 29, 2024
I was pleasantly surprised. The author did a great job wrapping everything up at the end. No weird plot holes left behind. A solid 5/5 for me.
Mark WhiteMay 10, 2025
Glad someone recommended this to me. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Definitely recommend it if you like this genre.
Michael HernandezJune 03, 2025
Took me a few chapters to get into it, but it was worth it. I liked the main character, though some of the side plots were just okay. I'd probably recommend it to a friend.
Kimberly GarciaNovember 17, 2024
A very satisfying read. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Would probably read it again at some point.
Jacob WilliamsJune 13, 2024
Pretty good overall. Writing is good, just wish there was a bit more depth in certain parts. Still kept my attention though. Not bad at all.
Kevin MillerSeptember 23, 2025
A very satisfying read. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Definitely recommend it if you like this genre.
Barbara NguyenNovember 09, 2025
Such a great read. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. Will be looking for more from this author.
Margaret MitchellDecember 16, 2025
I have mixed feelings about this one. It felt a bit repetitive in the middle. Could have been shorter. It's fine if you have nothing else to read.
Lisa SmithOctober 23, 2025
An average read for me. It had some good moments, but the overall plot felt a bit disjointed in the second half. A generous 3 stars.
Patricia TaylorJune 13, 2024
Took me a few chapters to get into it, but it was worth it. I liked the main character, though some of the side plots were just okay. I'd probably recommend it to a friend.
Sandra GonzalezJuly 21, 2025
A very satisfying read. I got really invested in the main character's journey. Everything just clicked for me. Glad I picked this up.
Mark GarciaFebruary 09, 2025
Good, but not quite perfect. Writing is good, just wish there was a bit more depth in certain parts. Still kept my attention though. Enjoyable weekend read.
Donald CampbellApril 21, 2025
Such a great read. I got really invested in the main character's journey. Everything just clicked for me. Worth the time and money.
Elizabeth BrownFebruary 02, 2024
An average read for me. The writing was fine, but I didn't feel very connected to the characters. They felt a bit flat. A generous 3 stars.
Carol PhillipsFebruary 12, 2025
Took me a few chapters to get into it, but it was worth it. Interesting premise and executed fairly well. Just a few slow chapters here and there. I'd probably recommend it to a friend.
David ParkerApril 11, 2024
A very satisfying read. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Glad I picked this up.
Rebecca RiveraOctober 11, 2025
Took me a few chapters to get into it, but it was worth it. It held my attention, even if a few things were a little predictable. A solid 4 stars from me.
Charles ParkerSeptember 02, 2024
Good, but not quite perfect. I liked the main character, though some of the side plots were just okay. Not bad at all.
Lisa BrownOctober 24, 2025
I have mixed feelings about this one. The pacing was a bit slow and I found myself skimming a few pages. It wasn't terrible, just okay. Might work better for someone else, just wasn't completely for me.
Charles CollinsMay 29, 2025
Good, but not quite perfect. The middle dragged a tiny bit, but the ending totally made up for it. I'd probably recommend it to a friend.
Donald WalkerMarch 10, 2025
Such a great read. I loved how the story unfolded. It kept me guessing without being too confusing. Would probably read it again at some point.
Nancy LopezFebruary 07, 2024
Pretty good overall. Interesting premise and executed fairly well. Just a few slow chapters here and there. I'd probably recommend it to a friend.
Stephanie ReyesNovember 23, 2025
Such a great read. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. A solid 5/5 for me.
Gary BakerDecember 26, 2024
Glad someone recommended this to me. I got really invested in the main character's journey. Everything just clicked for me. Definitely recommend it if you like this genre.
Michael BakerDecember 16, 2025
It was okay. It had some good moments, but the overall plot felt a bit disjointed in the second half. Might work better for someone else, just wasn't completely for me.
Kimberly PerezSeptember 26, 2024
Such a great read. I loved how the story unfolded. It kept me guessing without being too confusing. Will be looking for more from this author.
Elizabeth PhillipsNovember 28, 2024
A very satisfying read. I loved how the story unfolded. It kept me guessing without being too confusing. Worth the time and money.
Karen DiazOctober 29, 2024
Glad someone recommended this to me. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Glad I picked this up.
Laura CruzMarch 23, 2024
It was just alright. It had some good moments, but the overall plot felt a bit disjointed in the second half. Might work better for someone else, just wasn't completely for me.
Joshua LewisOctober 09, 2024
Such a great read. The pacing was spot on and the characters felt real. I didn't find myself getting bored at any point. Will be looking for more from this author.
Carol AdamsMay 07, 2025
Honestly one of the better books I've read lately. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Will be looking for more from this author.
James NguyenJune 04, 2024
A very satisfying read. I got really invested in the main character's journey. Everything just clicked for me. Worth the time and money.
Barbara BrownJanuary 20, 2025
Really enjoyed this one. I got really invested in the main character's journey. Everything just clicked for me. Would probably read it again at some point.
James NguyenMay 08, 2025
I was pleasantly surprised. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Will be looking for more from this author.
Gary WilsonJuly 04, 2025
Glad someone recommended this to me. The pacing was spot on and the characters felt real. I didn't find myself getting bored at any point. Definitely recommend it if you like this genre.
Jessica BakerNovember 07, 2025
Glad someone recommended this to me. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Glad I picked this up.
Ashley TurnerDecember 21, 2025
An average read for me. The pacing was a bit slow and I found myself skimming a few pages. It wasn't terrible, just okay. Might work better for someone else, just wasn't completely for me.
Lisa NguyenApril 17, 2025
An average read for me. The writing was fine, but I didn't feel very connected to the characters. They felt a bit flat. A generous 3 stars.
Jessica LewisDecember 02, 2024
It was okay. The pacing was a bit slow and I found myself skimming a few pages. It wasn't terrible, just okay. Just right down the middle.
Margaret ClarkMarch 19, 2025
A very satisfying read. The pacing was spot on and the characters felt real. I didn't find myself getting bored at any point. Would probably read it again at some point.
John LeeJanuary 25, 2025
Finished it in a couple of days. I loved how the story unfolded. It kept me guessing without being too confusing. A solid 5/5 for me.
Michael LeeDecember 08, 2025
I liked it for the most part. Interesting premise and executed fairly well. Just a few slow chapters here and there. Enjoyable weekend read.
Joshua RobertsDecember 04, 2024
Took me a few chapters to get into it, but it was worth it. It held my attention, even if a few things were a little predictable. Enjoyable weekend read.
Kimberly AdamsSeptember 08, 2025
Good, but not quite perfect. Interesting premise and executed fairly well. Just a few slow chapters here and there. I'd probably recommend it to a friend.
Thomas AndersonDecember 25, 2025
It was okay. It had some good moments, but the overall plot felt a bit disjointed in the second half. Just right down the middle.
Brian TorresAugust 24, 2024
Really enjoyed this one. I got really invested in the main character's journey. Everything just clicked for me. Worth the time and money.
George HillFebruary 24, 2024
Finished it in a couple of days. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Glad I picked this up.
Robert WrightFebruary 07, 2024
I liked it for the most part. The middle dragged a tiny bit, but the ending totally made up for it. Not bad at all.
Laura EvansNovember 12, 2025
Took me a few chapters to get into it, but it was worth it. I liked the main character, though some of the side plots were just okay. I'd probably recommend it to a friend.
William KingMay 05, 2025
A solid read. It held my attention, even if a few things were a little predictable. Not bad at all.
Elizabeth PhillipsMarch 15, 2025
Such a great read. The pacing was spot on and the characters felt real. I didn't find myself getting bored at any point. Would probably read it again at some point.
Betty LewisJanuary 18, 2025
A solid read. The middle dragged a tiny bit, but the ending totally made up for it. I'd probably recommend it to a friend.
Richard MitchellMay 24, 2024
Took me a few chapters to get into it, but it was worth it. It held my attention, even if a few things were a little predictable. Still a good book.
Kimberly GarciaAugust 24, 2025
Glad someone recommended this to me. The author did a great job wrapping everything up at the end. No weird plot holes left behind. Glad I picked this up.
Gary ScottJanuary 31, 2025
It was okay. It had some good moments, but the overall plot felt a bit disjointed in the second half. Just right down the middle.
Emily MillerNovember 29, 2025
I liked it for the most part. Writing is good, just wish there was a bit more depth in certain parts. Still kept my attention though. A solid 4 stars from me.
Linda CruzMarch 24, 2025
Finished it in a couple of days. I loved how the story unfolded. It kept me guessing without being too confusing. Worth the time and money.
William KingJune 30, 2024
Glad someone recommended this to me. It has a good balance of dialogue and description. Everything felt like it moved at the right speed. A solid 5/5 for me.
Matthew LopezOctober 19, 2025
Really enjoyed this one. The writing style is very engaging. It’s easy to follow but still has a lot of depth. Will be looking for more from this author.
Cynthia NelsonNovember 18, 2024
Pretty good overall. The middle dragged a tiny bit, but the ending totally made up for it. A solid 4 stars from me.
